Blar i forfatter "Andreassen, Kristine"

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    • Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy 

      Rixon, Chloe Louise; Andreassen, Kristine; Shen, Xin; Murugan Erusappan, Pugazendhi; Almaas, Vibeke Marie; Palmero, Sheryl; Dahl, Christen Peder; Ueland, Thor; Sjaastad, Ivar; Louch, William Edward; Stokke, Mathis Korseberg; Tønnessen, Theis; Christensen, Geir; Lunde, Ida Gjervold (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-29)
      Aims Familial hypertrophic cardiomyopathy (HCM) is the most common form of inherited cardiac disease. It is characterized by myocardial hypertrophy and diastolic dysfunction, and can lead to severe heart failure, arrhythmias, and sudden cardiac death. Cardiac fibrosis, defined by excessive accumulation of extracellular matrix (ECM) components, is central to the pathophysiology of HCM. The ECM ...

    • Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study 

      Myklebust, Mette Pernille; Thor, Anna; Rosenlund, Nina Benedikte; Gjengstø, Peder; Karlsdottir, Åsa; Brydøy, Marianne; Bercea, Bogdan Stefan; Olsen, Christian; Johnson, Ida; Berg, Mathilde I.; Langberg, Carl; Andreassen, Kristine; Kjellman, Anders; Haugnes, Hege Sagstuen; Dahl, Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)
      MicroRNA-371a-3p (miR371) has been suggested as a sensitive biomarker in testicular germ cell cancer (TGCC). We aimed to compare miR371 with the classical biomarkers α-fetoprotein (AFP) and β-human chorionic gonadotropin (hCG<sub>β</sub>). Overall, 180 patients were prospectively enrolled in the study, with serum samples collected before and after orchiectomy. We compared the use of digital droplet ...